Reduced Skin Capillary Density During Attacks of Erythromelalgia Implies Arteriovenous Shunting as Pathogenetic Mechanism
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چکیده
منابع مشابه
Reduced skin capillary density during attacks of erythromelalgia implies arteriovenous shunting as pathogenetic mechanism.
Erythromelalgia is characterized by burning pain, erythema, and increased temperature in acral skin. The pain is aggravated by warming and relieved by cooling. Increased microvascular arteriovenous shunting in deep dermal plexa has been hypothesized as the pathogenetic mechanism of pain in affected skin, inducing hypoxia during pain attacks. The aim of this study was to quantify skin capillary ...
متن کاملMicrovascular arteriovenous shunting is a probable pathogenetic mechanism in erythromelalgia.
Erythromelalgia is a condition consisting of red, warm, and burning painful extremities. Symptoms are relieved by cold and aggravated by heat. A wide variety of etiologic conditions can cause erythromelalgia, but one common pathogenetic mechanism, microvascular arteriovenous shunting, has been hypothesized. The aim of this study was to test this hypothesis. Quantification of skin microvascular ...
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Chapter 1 Introduction Erythromelalgia (EM) is a rare disorder characterized by red, warm and painful extremities. In what superficially appears to be the antithesis of Raynaud's disease, victims of EM seek relief by cooling of the affected extremity. Over the years terms such as erythermalgia [1], and erythralgia [2] have also been used for the condition. Graves [3] reported the first case of ...
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Erythromelalgia is a clinical diagnosis characterized by erythema, increased temperature and burning pain in acral skin. The pain is relieved by cooling and aggravated by warming. The symptoms have been hypothesized to be caused by skin hypoxia due to increased arteriovenous shunting. We examined skin microvascular perfusion in response to vasoconstrictory and vasodilatory stimuli, to character...
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Based on previous experience with parenteral prostanoids, we studied the effect of misoprostol treatment, an orally administered prostaglandin E1 analog, in patients with erythromelalgia. Treatment with placebo was followed by treatment with misoprostol (0.4-0.8 mg per d), both for 6 wk. The patients (n=21) and a study nurse who administered the trial were blinded. The endpoints were change in ...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2002
ISSN: 0022-202X
DOI: 10.1046/j.1523-1747.2002.00218.x